Irf3 molecular weight
WebSynthetic peptide corresponding to Human IRF3 (phospho S386). Database link: Q14653 Positive control WB: MCF7 cells treated with Calyculin A. General notes This product is a … WebFeb 26, 2024 · Nsp12 did not impair IRF3 phosphorylation but suppressed the nuclear translocation of IRF3. ... After 24 h, the cells were stimulated with SeV or high-molecular weight poly(I:C) (HMW-poly[I:C]), ...
Irf3 molecular weight
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WebMolar mass of IrF3 = 249.2122096 g/mol Convert grams Iridium (III) Fluoride to moles or moles Iridium (III) Fluoride to grams Molecular weight calculation: 192.217 + 18.9984032*3 Percent composition by element Similar chemical … WebKey component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR3 is a nucleotide-sensing TLR which is activated by double-stranded RNA, a sign of viral infection.
WebJan 4, 2024 · To determine the molecular mechanism by which UAP1 promotes type I IFN signaling, ... (20 mg/kg body weight [BW]) ... Total lysates were prepared from IRF3 KO HEK293T cells transfected with Flag-IRF3 and followed by immunoprecipitation with α-Flag M2 beads. Immunoprecipitated proteins were separated by SDS-PAGE, and then stained … WebAug 10, 2024 · Introduction. Interferon regulatory factor 9 (IRF9) was first discovered as part of a protein subunit purified from the interferon-stimulated gene factor 3 (ISGF3) complex ().Early studies have referred IRF9 as ISGF3γ and p48—due to its molecular weight of 48 kDa (1–4).IRF9 is best characterized as a transcription factor that mediates (as part …
WebJul 1, 2014 · Abstract. TBK1 (TANK-binding kinase 1) is a noncanonical IκB protein kinase that phosphorylates and activates downstream targets such as IRF3 and c-Rel and, mediates NF-κB activation in cancer. Previous reports demonstrated synthetic lethality of TBK1 with mutant KRAS in non–small cell lung cancer (NSCLC); thus, TBK1 could be a novel target … WebProduct Specific Information This antibody detects endogenous protein at a molecular weight of 47 and 55 kDa. Purity is >95% by SDS-PAGE. Target Information IFR3 (interferon regulatory factor 3) is a key transcriptional …
WebKey features and details Rabbit polyclonal to IRF3 (phospho S396) Suitable for: WB Reacts with: Human Isotype: IgG You may also be interested in Primary Anti-IRF3 (phospho S386) antibody [EPR2346] - BSA and Azide free (ab182859) Protein Recombinant Human IRF3 protein (ab205216) Secondary Goat Anti-Rabbit IgG H&L (HRP) (ab205718)
WebNov 26, 2024 · R848 and cpGB were obtained from InvivoGen (San Diego, CA) and high molecular weight poly(I:C) from Sigma-Aldrich, P1530 (St. Louis, MO). Recombinant M-CSF and GM-CSF were purchased from Pepro Tech (Cranbury, NJ). ... (n = 4). b Mda5, c Irf1, d Irf3, e Irf7, f Irf8, and g Irf9. Assays are representative of at least three independent … great grandmother of queen elizabeth 11http://www.endmemo.com/chem/compound/fef3.php flix movie schedule todayWebApr 28, 2024 · Immunoblotting experiments indicated that phosphorylation of IRF3 S386, ... Immunoblotting experiments indicated that the molecular weight of cGAS in mitotic cells … great grandmother of rizalWebMar 10, 2011 · Regardless of this technical point, the clear presence of a high molecular weight band demonstrates that PU.1 is an additional DNA binding factor at the IFN-β … flix movies carmel inWebDec 4, 2024 · IRF3 and IRF5 are phosphorylated by protein kinases, which are activated by signalling pathways of pattern recognition receptors (PRRs), including Toll-like receptors (TLRs) that signal via TRIF (TLR3 and TLR4) and MyD88 (e.g. … flix movies in lancaster nyWebMay 15, 2016 · IFN regulatory factor 3 (IRF3) is the master transcription factor that controls IFN-I production via phosphorylation-dependent dimerization in most cell types in response to viral infections and various innate stimuli by … great grandmother of rizal on his mother sideWebNational Center for Biotechnology Information flix movie showtimes