Foxm1 rfc
WebSep 12, 2024 · FOXM1 maintains cancer hallmarks by regulating the expression of target genes at the transcriptional level. Due to its potential … WebOct 3, 2014 · FOXM1 is a transcription factor required for a wide spectrum of essential biological functions, including DNA damage repair, cell proliferation, cell cycle progression, cell renewal, cell...
Foxm1 rfc
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WebJul 14, 2024 · FOXM1 transcription factor is an oncogene and a master regulator of chemoresistance in multiple cancers. Pharmacological inhibition of FOXM1 is a promising approach but has proven to be... WebNature Rev. Cancer 7, 847–859) 1. The authors discuss our recent work on the identification of the thiazole antibiotic siomycin A as an inhibitor of FOXM1 function 2. However, they incorrectly ...
WebOct 3, 2014 · FOXM1 is a transcription factor required for a wide spectrum of essential biological functions, including DNA damage repair, cell proliferation, cell cycle … WebFeb 9, 2009 · FoxM1 is a member of the Forkhead family of transcription factors and is implicated in inducing cell proliferation and some forms of tumorigenesis. It binds promoter regions with a preference for tandem …
WebMay 5, 2024 · FOXM1 is a known proto-oncogene that is implicated in cellular proliferation, cell cycle progression, cell differentiation, DNA damage repair, tissue homeostasis, …
WebFOXM1. Forkhead box protein M1 is a protein that in humans is encoded by the FOXM1 gene. [5] [6] The protein encoded by this gene is a member of the FOX family of transcription factors. [5] [7] Its potential as a target for future cancer treatments led to it being designated the 2010 Molecule of the Year. [8]
WebMar 21, 2024 · FOXM1 (Forkhead Box M1) is a Protein Coding gene. Diseases associated with FOXM1 include Hepatocellular Carcinoma and Protein C Deficiency. Among its … family practice in chesapeake vaWebFeb 1, 2024 · Our results showed that FoxM1 promotes cell proliferation by upregulating STMN1. Further ChIP assay showed that FoxM1 upregulates STMN1 in a transcriptional level. Prognostic analysis showed... family practice in corpus christiWebJun 11, 2024 · The relapse-free survival rate tended to be lower in PDAC cases with the expression of both DKK1 and FOXM1 compared to other cases (cases positive for either DKK1 or FOXM1 alone or negative for ... family practice in front royal vaWebDec 22, 2024 · Structure of human FOXM1 gene, mouse Foxm1 gene, mutant of human gene FOXM1 (hFOXM1 exon9), and mutant mouse gene Foxm1 (mFoxm1 +hexon9). Cell immunostaining for HOPX in control, hFOXM1-FL, and mutants in mice primary neural progenitors 3 days following lentiviral infection. White arrows represent GFP HOPX … family practice in elysburg paWebNov 6, 2012 · Abstract. Purpose: Recurrent glioblastoma multiforme (GBM) is characterized by resistance to radiotherapy and chemotherapy and a poor clinical prognosis. In this study, we investigated the role of the oncogenic transcription factor FoxM1 in GBM cells' resistance to alkylator temozolomide (TMZ) and its potential molecular mechanism.Experimental … family practice in gainesville flWebFeb 9, 2024 · We showed that RFC5 expression is positively correlated with FoxM1 expression in human glioma cells and FoxM1 is able to transcriptionally activate RFC expression by interaction with the RFC5 promoter. Furthermore, knockdown of FoxM1 or RFC5 partially re-sensitizes glioma cells to TMZ. coolidge corner restaurants brookline maWebFeb 9, 2024 · FoxM1 regulates RFC5 expression through interaction with RFC5 promoter Using GeneQuest (Lasergene 7.1), we identified two potential FoxM1-binding motifs, i.e., 5′-GTTTGT-3′ and 5′-CAAATA-3′ … family practice in goochland va