WebFeb 20, 2024 · Cisplatin is a platinum-based anticancer drug widely used to treat various types of cancer and contributes to the improvement in outcomes like 5-year survival. However, side effects of cisplatin including ototoxicity, neurotoxicity, nausea, and myelosuppression frequently occur, and the main dose-limiting side effect is … WebJan 7, 2024 · Data on the following variables were recorded: age, sex, diagnosis, height, weight, mannitol treatment, cisplatin treatment (number of treatments and absolute dose), hypertension (current antihypertensive treatment), diabetes, use of acetylsalicylic acid, use of angiotensin-converting enzyme (ACE)-inhibitors, tobacco use, exposure to ...
Cisplatin Neurotoxicity Presenting as Reversible Posterior ...
WebBackground A strategy for preventing cisplatin nephrotoxicity due to enhanced oxidative stress and inflammatory response is highly desirable. Thioredoxin-1 (Trx), an endogenous redox-active protein, WebApr 12, 2024 · A 63-year-old woman who was a former smoker with a past medical history of hypertension and gastroesophageal reflux disease initially presented with upper abdominal pain. ... was 8 and 5 months in the cisplatin plus gemcitabine cohort and the gemcitabine cohort (p < .001), respectively. 4 Based on the phase 3 ABC-02 trial, cisplatin and ... can irobot clean stairs
Chemotherapy side effects: A cause of heart disease?
Webities, hypertension, and proteinuria (Table 1). AGENTS WITH PREDOMONANLTY TUBULAR TOXICITY Platinum compounds Cisplatin(cis-dichlorodiammineplatinum)–platinum coordination complex is an effective chemotherapy against a wide spectrum of tumors such as testicular, head and neck, ovarian, lung, … http://www.ajnr.org/content/ajnr/19/3/415.full.pdf WebCisplatin is one of the most broadly used chemotherapeutic agents. Several central nervous system toxicities have been attributed to this agent, among which is a rare clinicoradiological condition referred to as posterior reversible leukoen-cephalopathy syndrome (PRES) or reversible posterior leukoencephalopathy syndrome (RPLS). can irobot filters be washed