Chitinase-3-like protein 1

Author: jbao

August undefined, 2024

WebJohansen and Carretta et al. found that COS exerted their anti-tumorigenic effects through the inhibition of YKL-40 (also known as chitinase-3-like 1 or Chi3L1), which is a conserved, secreted chitinase-like protein (CLP) found in elevated levels in many diseases, including cancer [126,127]. WebDiagnosis of cardiac surgery-associated acute kidney injury: differential roles of creatinine, chitinase 3-like protein 1 and neutrophil gelatinase-associated lipocalin: a prospective cohort study

Chitinase 3-like 1 protein plays a critical role in respiratory ...

WebApr 6, 2024 · IntroductionPositive intracranial arterial remodelling is a dilated lesion of the large intracranial vessels; however, its pathogenesis is currently unknown. Some studies … WebChitinase 3-like 1 (CHI3L1) is a chitinase-like protein, which affects cel … The cancer‑stromal interaction has been demonstrated to promote tumor progression, and … dew drop inn mason city il

Intact regulation of muscle expression and circulating levels of ...

WebJul 6, 2024 · Here, we show that chitinase-3-like 1 (CHI3L1), also known as human homolog YKL-40, predominately modulates the GBM TME using unbiased approaches. CHI3L1 signaling selectively regulates tumor infiltration and cell migration of MDMs and MG by forming distinct protein-binding complexes. WebMar 2, 2024 · Chitinase-3-like protein 1 (CHI3L1/YKL-40) has long been known as a biomarker for early detection of neuroinflammation and disease diagnosis of Alzheimer's disease (AD). In the brain, CHI3L1 is primarily provided by astrocytes and heralds the reactive, neurotoxic state triggered by inflammation and other stress signals. ... WebApr 6, 2024 · IntroductionPositive intracranial arterial remodelling is a dilated lesion of the large intracranial vessels; however, its pathogenesis is currently unknown. Some studies have identified chitinase-3 like-protein-1 (YKL-40) and matrix metalloproteinase (MMP)-9 as circulating inflammatory factors involved in positive vascular remodelling. Herein, we … dew drop inn cleves ohio

Chitinases and Chitinase-Like Proteins in Obstructive Lung …

Animals Free Full-Text Comparative Proteomic Analysis …

WebMar 4, 2024 · Chitinase-3-like protein 1 (CHI3L1) was induced in both acute and chronic liver injuries, and recent studies reported that it possesses an immunosuppressive ability. CHI3L1 was also expressed in mesenchymal stem cells (MSCs), thus we investigates the role of CHI3L1 in MSC-based therapy for immune-mediated liver injury here. We found … WebDiagnosis of cardiac surgery-associated acute kidney injury: differential roles of creatinine, chitinase 3-like protein 1 and neutrophil gelatinase-associated lipocalin: a prospective … dew drop inn new crossWebChitinase-3-Like Protein 1 Cysteine-Rich Protein 61 Cytokines IL15 protein, human IL6 protein, human Interleukin-15 Interleukin-6 Muscle Proteins fibroblast growth factor 21 Connective Tissue Growth Factor Fibroblast Growth Factors ... dew drop inn hathern

"WebChitinase-3-Like Protein 1. YKL-40, a 40 kDa plasma protein, is the best-known protein from the CLPs group. YKL-40 lacks chitinolytic activity due to the mutation of glutamic … " - Chitinase-3-like protein 1

Chitinase-3-like protein 1

WebChitinase 3-like 1: Products. Chitinase 3-like 1 (CHI3L1), also called BRP39 in mouse or YKL-40 in humans, is a 39 kDa glycoprotein member of the glycosyl hydrolase 18 family although it does not show chitotriosidase activity. CHI3L1 is expressed by articular chondrocytes, synovial cells, activated monocyte-derived macrophages, neutrophils ... WebApr 5, 2024 · Chitinase-3-like protein 1 is an independent risk factor for the early failure of forearm autologous arteriovenous fistulas in uremic patients. Chitinase 3-like-1, Tolloid-like protein 1, and intergenic gene polymorphisms are predictors for hepatocellular carcinoma development after hepatitis C virus eradication by direct-acting antivirals.

Did you know?

WebUrine chitinase 3-like. Background Acute kidney injury (AKI) is a frequently occurring syndrome in critically ill patients and is associated with worse outcomes. Biomarkers … WebChitinase 3-like 1 (CHI3L1) is a secreted glycoprotein that mediates inflammation, macrophage polarization, apoptosis, and carcinogenesis. The expression of CHI3L1 is …

WebNo chitinase activity. Essential for normal plant growth and development. Regulates cell expansion extent and differentiation at least in roots and hypocotyls. Prevents lignin … WebAnti-Chitinase-3-like protein 1 (YKL-40) Antibody, clone mAY. Compare Product No. Clonality Application Species Reactivity Citations SDS; MABC196: mAY, monoclonal: IHC, WB, activity assay: human: 6: Expand. Hide. Match Criteria: Product Name, Keyword. All Photos (1) Human CHI3L1 / Chitinase-3-like Protein 1 ELISA Kit. Compare Product No ...

WebChitinase 3-like 1: Products. Chitinase 3-like 1 (CHI3L1), also called BRP39 in mouse or YKL-40 in humans, is a 39 kDa glycoprotein member of the glycosyl hydrolase 18 family … WebChitinase-3-like protein 1 (YKL-40, also named human cartilage glycoprotein 39) is a mammalian glycoprotein related in sequence to family 18 of bacterial and fungal …

WebMar 8, 2024 · Chitinase-3-like 1 protein (YKL-40) is a secreted glycoprotein originally isolated from human osteosarcoma cells . YKL-40 is approximately 40 kDa in size and is …

WebThe human homologue chitinase 3-like protein 1 was found to be more excreted in urine from septic patients with AKI than without. In summary, urinary chitinase 3-like protein 1 and -3 and acidic mammalian chitinase discriminated sepsis from sepsis-induced AKI in mice. Further studies of human chitinase proteins are likely to lead to additional ... dew drop inn peacehavenWebAug 1, 2024 · Frequency of M1/M2-like MDMs ( G) and CD8 + T cells with expression of PD-1 and CTLA-4 ( H) in tumors derived from syngeneic mice bearing GL261-CHI3L1 under treatment with GMP versus SCP. Each dot represents 1 mouse; data are presented as the mean ± SEM. P values were calculated using a 1-tailed, unpaired t test. dew drop inn lyricsWebFeb 1, 2024 · The differentially secreted proteins of M1 and M2 macrophages were analyzed by mass spectrometry. We performed GST pull-down assay for the identification of cell-membrane receptors that interact with chitinase 3-like protein 1 (CHI3L1) protein. The mouse model was used to validate the function of CHI3L1 in cancer metastasis in vivo. church of the first miracle canaWebBackground: Chitinase 3-like 1 protein (CHI3L1) (YKL-40 in humans and breast regression protein [BRP]-39 in mice) is required for optimal allergen sensitization and Th2 inflammation in various chronic inflammatory diseases including asthma. However, the role of CHI3L1 in airway inflammation induced by respiratory viruses has not been investigated. dew drop inn shillongWebChitinase-3-Like Protein 1. YKL-40, a 40 kDa plasma protein, is the best-known protein from the CLPs group. YKL-40 lacks chitinolytic activity due to the mutation of glutamic acid to leucine in the chitinase-3-like catalytic domain. 27 The expression of YKL-40 was found in different mammalian organs and tissues (ie, ... church of the foothills sylmar caWebIntroduction. Chitinase-3-like protein 1 (CHI3L1), also known as YKL-40 and human cartilage glycoprotein-39 (HC-gp39), is a highly conserved glycoprotein that can bind to … church of the final judgmentWebChitinase-3-like protein 1 (CHI3L1), also known as YKL-40, is a secreted glycoprotein that is approximately 40kDa in size that in humans is encoded by the CHI3L1 gene. The name YKL-40 is derived from the three N … church of the flying spaghetti monster book